Prolonged neuromuscular block following accidental subcutaneous injection of vecuronium
نویسندگان
چکیده
منابع مشابه
Mivacurium-induced prolonged neuromuscular block.
We report a case of prolonged neuromuscular block after administration of mivacurium 0.2 mg kg-1 to a 16-yr-old patient where the duration of block was 2.5 h. The interesting points in this case were that the patient had homozygous atypical plasma cholinesterase deficiency (both parents had a normal phenotype) following liver transplantation. Investigations showed low plasma cholinesterase acti...
متن کاملProlonged vecuronium neuromuscular blockade associated with Charcot Marie Tooth neuropathy.
Charcot Marie Tooth (CMT) disease comprises a group of disorders characterized by progressive distal muscle weakness and wasting. Review of the anaesthetic literature produced conflicting reports concerning the responses to neuromuscular blocking drugs in these patients. We describe a case in which vecuronium 0.11 mg kg(-1) produced prolonged neuromuscular blockade lasting 115 min in a patient ...
متن کاملThe use of sugammadex for the reversal of vecuronium-induced neuromuscular block following intracranial surgery.
BACKGROUND Total intravenous anaesthesia with propofol and remifentanil is widely used in neuroanaesthesiology and enables the quick recovery and early neurological assessment of patients. The administration of muscle relaxants carries a risk of residual relaxation following surgery. The administration of a suitable dose of sugammadex reverses the neuromuscular block irrespective of its depth a...
متن کاملParadoxical antagonism of neuromuscular block by vecuronium metabolites.
Vecuronium is hydrolyzed in the body to 3-deacetyl (ORG 7268), 17-deacetyl (ORG NC58), and 3, 17-bis-deacetyl (ORG 7402) derivatives. Interactions of vecuronium and these metabolites were studied in phrenic nerve-hemidiaphragm preparations of rats. As already reported, ORG 7268 had a potent neuromuscular blocking action, and ORG NC58 and ORG 7402 had a weak neuromuscular blocking action. As exp...
متن کاملVecuronium neuromuscular block in patients with malignant obstructive jaundice.
when the infant demonstrated adequate tone and wakefulness. Upon arrival in the PACU, the infant's temperature was 36.4~ respiratory rate 30-35 per minute, heart rate 180-190 bpm, and the SpO2 was 100% breathing 0.4 FIO2. The infant's nurse, noting that the/v solution was not infusing, injected saline through an injection port. 'Approximately ten minutes later, the patient's cry began to weaken...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 2011
ISSN: 0003-2409
DOI: 10.1111/j.1365-2044.2011.06870.x